Mesotherapy is one of the very popular aesthetic procedures. Before applying the mesotherapy process, the needs, age and health condition of the person are checked on basis of which the suitable substances such as amino acids, enzymes, hormones, minerals, vitamins, antioxidants and hyaluronic acid are prepared. These prepared substances are applied to the skin where it is needed with the mesotherapy process. These substances which are applied to the skin tissue stimulate the structures called collagen and elastin that keep the skin alive and tight. These stimulated structures accelerate the blood circulation in the area applied and provide the regulation of the immune response and circulation in the lymphatic system. All these things together provide skin renewal. Subcutaneous tissue is repaired and thus the loosened tissues regain their old firmness and rejuvenation is provided. The results and success rates vary depending on factors such as the number of sessions, the correct ratio of injected substances and the person himself.